Sh\u00ebrbimi Sh\u00ebndet\u00ebsor Komb\u00ebtar n\u00eb Angli ka miratuar p\u00ebrdorimin e nj\u00eb ila\u00e7i nga i cili mund t\u00eb p\u00ebrfitojn\u00eb qindra pacient\u00eb me kancer gjiri dhe kancer t\u00eb prostat\u00ebs<\/p>\n
Burrat me kancer t\u00eb avancuar t\u00eb prostat\u00ebs dhe grat\u00eb me kancer t\u00eb hersh\u00ebm t\u00eb gjirit HER2-negativ q\u00eb jan\u00eb n\u00eb rrezik t\u00eb lart\u00eb t\u00eb rikthimit t\u00eb s\u00ebmundjes do t\u00eb jen\u00eb n\u00eb gjendje t\u00eb p\u00ebrdorin olaparib p\u00ebrmes NHS (Sh\u00ebrbimi Sh\u00ebndet\u00ebsor Komb\u00ebtar) n\u00eb Angli.<\/p>\n
Olaparib, i cili jepet si tablet\u00eb, \u00ebsht\u00eb nj\u00eb lloj ila\u00e7i i synuar i quajtur frenues Parp. K\u00ebto parandalojn\u00eb riparimin e qelizave kancerogjene.<\/p>\n
Ila\u00e7i synon kanceret me mutacione BRCA 1 ose BRCA 2 dhe funksionon duke ndaluar qelizat e kancerit t\u00eb jen\u00eb n\u00eb gjendje t\u00eb riparojn\u00eb ADN-n\u00eb e tyre, gj\u00eb q\u00eb shkakton vdekjen e qelizave kancerogjene.<\/p>\n
Provat klinike kan\u00eb treguar se olaparib, i njohur gjithashtu si Lynparza dhe i prodhuar nga firma farmaceutike AstraZeneca, mund t\u00eb zgjas\u00eb jet\u00ebn e pacient\u00ebve me kancer t\u00eb avancuar t\u00eb prostat\u00ebs me \u2018mesatarisht gjasht\u00eb muaj\u2019, tha NHS England.<\/p>\n
Vler\u00ebsohet se rreth 550 burra me kancer t\u00eb avancuar t\u00eb prostat\u00ebs dhe 300 gra me kancer t\u00eb hersh\u00ebm t\u00eb gjirit HER2-negativ do t\u00eb ken\u00eb t\u00eb drejt\u00eb p\u00ebr ila\u00e7in e ri \u00e7do vit n\u00eb Angli.<\/p>\n
\u201cOlaparib mund t\u00eb ket\u00eb nj\u00eb ndikim t\u00eb madh te pacient\u00ebt me nj\u00eb s\u00ebr\u00eb llojesh kanceri, duke u dh\u00ebn\u00eb njer\u00ebzve nj\u00eb shans m\u00eb t\u00eb mir\u00eb p\u00ebr t\u00eb mbijetuar, nd\u00ebrkoh\u00eb q\u00eb u ofron atyre me forma t\u00eb avancuara t\u00eb s\u00ebmundjes, muaj shtes\u00eb p\u00ebr t\u00eb jetuar\u201d, tha shefja ekzekutive e NHS Angli, Amanda Pritchard.<\/p>\n
Ekspert\u00ebt n\u00eb Institutin e K\u00ebrkimit t\u00eb Kancerit (ICR) e p\u00ebrshkruan vendimin si \u201cndryshues t\u00eb jet\u00ebs\u201d dhe thon\u00eb se ila\u00e7i u jep pacient\u00ebve nj\u00eb shans p\u00ebr t\u00eb jetuar jet\u00eb m\u00eb t\u00eb gjat\u00eb dhe m\u00eb t\u00eb sh\u00ebndetshme.<\/p>\n
Johann De Bono, profesor n\u00eb mjek\u00ebsin\u00eb eksperimentale t\u00eb kancerit n\u00eb ICR, tha: Olaparib \u00ebsht\u00eb nj\u00eb shembull i r\u00ebnd\u00ebsish\u00ebm se si t\u00eb kuptuarit e gjenetik\u00ebs themelore t\u00eb pacient\u00ebve dhe gjenomik\u00ebs s\u00eb tumoreve t\u00eb tyre, mund t\u00eb p\u00ebrdoret p\u00ebr t\u00eb hartuar ila\u00e7e me precizion shum\u00eb t\u00eb synuar. P\u00ebr pacient\u00ebt me kancer t\u00eb avancuar t\u00eb prostat\u00ebs dhe mutacione n\u00eb BRCA1 ose BRCA2, k\u00ebto rekomandime do t\u00eb ndryshojn\u00eb jet\u00ebn. \/Telegrafi\/<\/p>\n","protected":false},"excerpt":{"rendered":"
Sh\u00ebrbimi Sh\u00ebndet\u00ebsor Komb\u00ebtar n\u00eb Angli ka miratuar p\u00ebrdorimin e nj\u00eb ila\u00e7i nga i cili mund t\u00eb p\u00ebrfitojn\u00eb qindra pacient\u00eb me kancer gjiri dhe kancer t\u00eb<\/p>\n","protected":false},"author":14,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[50],"tags":[],"class_list":["post-3282","post","type-post","status-publish","format-standard","hentry","category-kuriozitete"],"_links":{"self":[{"href":"https:\/\/indeks.bilten.mk\/index.php?rest_route=\/wp\/v2\/posts\/3282","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/indeks.bilten.mk\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/indeks.bilten.mk\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/indeks.bilten.mk\/index.php?rest_route=\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/indeks.bilten.mk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3282"}],"version-history":[{"count":0,"href":"https:\/\/indeks.bilten.mk\/index.php?rest_route=\/wp\/v2\/posts\/3282\/revisions"}],"wp:attachment":[{"href":"https:\/\/indeks.bilten.mk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3282"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/indeks.bilten.mk\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3282"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/indeks.bilten.mk\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3282"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}